FLUID BED DRYER
There are a few distinct things you should take into account when determining whether a Fluid Bed Dryer is the best option for your powder processing needs. These elements consist of process parameters, expansion chamber, and flowability. Learn more by reading on. The benefits and drawbacks of each of these qualities are discussed in this article.
WHAT IS FLOWABILITY IN FLUID BED DRYER?
When developing a new tablet compression technique, fluid bed granulation’s flowability is a crucial component. By adjusting the temperature and binder concentration during mixing and drying, this procedure can be made more effective. Commonly, this process exhibits well defined critical parameters. The best variables from the first set of studies were used in the second set of experiments to maximize granulation. Then, in order to investigate a new design space and gauge their impact on the finished tablet, the atomization pressure and the compression force were modified.
WET GRANULATION WITH FLUID BED GRANULATION
A variety of powders can be processed using the fluidized-bed granulation method, which is a very straightforward technique. In this method, liquids are aggregated using an air stream. After that, size and porosity are used to segregate the created particles. Fluidized-bed granulation is an excellent option for a variety of applications because of these qualities. But it’s crucial to choose the right granulation method based on the characteristics of the raw powder material and binder liquid.
To keep the powder bed fluidized and stop material from leaving, a fluidized bed granulator is used. From a draught tube towards the bottom, liquid binder is sprayed onto the bed. Granules form as solid particles join the liquid droplets. To guarantee a constant partial drying process throughout the granulation process, fluidizing air is required.
WHAT IS EXPANSION CHAMBER IN FLUID BED DRYER?
The expansion chamber wall is ideally supplied with a thermocouple probe. In the industry, the highest air-to-cloth ratio is offered by full-length filter bags. They are automatically pulsed clean, resulting in lower working temperatures, higher yields, and quicker cleanup. They are set up in the top part of the expansion chamber, and they are pulsed clean to enable continuous fluidization. Most Fluid Bed Granulators can use full-length filter bags.
WHAT ARE PROCESS PARAMETERS OF FLUID BED DRYER?
When assessing the process parameters for a Fluid Bed Granulator, there are numerous things to take into account. The process parameters are typically estimated based on the assumption of a constant bed depth. The bed depth increases together with the size of the production. This element is crucial for both production batch sizes and design batch sizes. However, there is no linear link between scale-up parameters and bed depth. As a result, it is necessary to base process parameters, including air volume, on eye inspection.
Granules created by fluidized bed granulation are distinct from those created by other wet granulation techniques. The characteristics of the raw powder material and the binder liquid must be taken into account when choosing the granulation technique to use. Larger granules are produced when the liquid flow rate exceeds one liter per second. A nozzle height that completely covers the bed’s surface is appropriate. The bed will be wetted if the nozzle is too low or high, which will slow down the granulation process.
HOW MONITORING IS DONE IN FLUID BED DRYER?
A new technique for assessing the efficiency of fluid bed granulators has been made possible by the creation of a procedure for the granulation of coated tablets. Spraying a binder liquid onto fluidizing powder particles causes them to collide and create larger, more durable aggregates during the fluid bed granulation process. Following this procedure, a fluid bed granulator swiftly dries the moist granules. A variety of analytical process sensors have been used for the in-line monitoring of granule moisture content.
This approach enables real-time monitoring of particle size and moisture. For monitoring and modifying the process parameters, the spectrometer also offers real-time moisture measurements. To assess granule behavior, the collected data can also be connected with temperature and moisture profiles. With the help of these technologies, users may reduce variability and personalize the monitoring of granulator activities.
THE BOTTOM LINE
You can increase productivity while lowering the cost of producing powder with a fluid bed granulator. The benefits and drawbacks of fluid bed granulators have been thoroughly covered above. Granulators can be used in fluid bed granulators in the chemical, food, and pharmaceutical industries to granulate, coat, and pelletize a variety of materials.