Automatic Ampoule Filling & Sealing Machine

The Automatic Ampoule Filling & Sealing Machine is made specifically for filling and sealing glass ampoules for pharmaceutical, biotech, cosmetic, and chemical industries.

Sterile Construction for Critical Environments

Fabricated from SS 316L contact parts, the entire Automatic Ampoule Filling & Sealing Machine is made of stainless steel construction, built in accordance with GMP and FDA standards. The seamless design provides a reduced contamination risk and is compatible with cleanroom integration and easy sterilization, allowing compliance with aseptic manufacturing protocols.

Automatic Ampoule Filling & Sealing Machine Video

How It Works?

• Infeed hopper: The sterile ampoules are put in the infeed hopper.

• Star Wheel: A starwheel then transfers them into the transport rack, which conveys them through stations

• Pre-Gassing: Nitrogen gas is pumped into the ampoule to purge oxygen.

• Filling: The liquid product is accurately filled into the ampoule.

• Post-gassing: Additional nitrogen flush for further product protection.

• Ampoule neck: The ampoule neck is heated before sealing.

• Sealing: The ampoule is hermetically sealed with a flame to maintain product sterility.

​

Key Features of Ampoule Filling & Sealing Machine

• GMP compact design: Design conforms to current Good Manufacturing Practices, focusing on product quality and safety. All contact parts are made from High-Quality SS316L, and Non-contact parts are made from SS304.

• High Throughput: Configuration-dependent up to 6,000 ampoules per hour

• Versatile Ampoule Range: Capable of working with ampoules from 1ml to 30ml that require very little in changeover parts.

• No Ampoule–No Filling: Avoids wastage by ensuring filling only takes place when ampoules are available.

• Ampoules Neck Centering: Enables accurate gas flushing and filling processes.

• Nitrogen Flushing Options: Providing nitrogen gas flushing before, during, and after the filling of your product to ensure product integrity.

• Pre-Warming Station: A station that can prepare ampoules before the sealing; the equipment allows for secure closure of the ampoule.

• Flame regulation: Flow meters make it easy to adjust the sealing flames.

• Quick Changeover Time: To optimize operation time, it has been designed to adapt quickly to different sizes of ampoules.

• Filling Mechanism: It offers three different types of filling, namely Piston Pump Filling, Servo-Driven Filling, and Peristaltic Pump Filling.

• Certification and Compliance: Models are also available upon request that are CE certified and 21 CFR Part 11 compliant.

• Combi Machine Availability: Open and closed-mouth ampoules can both be handled by the machinery.

Technical Highlights

Common Specifications (All Models)

• Filling Precision: ±1%

• Filling Pump Type: Piston pump (other options like peristaltic and servo available on request)

• Sealing System: Flame sealing using LPG & Oxygen (O₂)

• Nitrogen Flushing: Available before, during, and after filling

• Power Voltage: 230 Volts, Single Phase, 50 Hz, 4-Wire System

• Contact Parts Material: Stainless Steel 316L

• Construction: Compact GMP-compliant stainless steel structure

• Suitable Ampoule Type: Open-mouth glass ampoules

• Filling and Sealing Stations: Integrated monoblock platform

• Changeover: Quick, tool-free adjustment for different ampoule sizes

CE & 21 CFR Part 11 compliance: Available upon request

Technical Specification of Ampoule Filling & Sealing Machine

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

The Automatic Ampoule Filling & Sealing Machine exemplifies Adinath’s commitment to delivering high-quality, efficient, and user-friendly pharmaceutical machinery, ensuring optimal performance and compliance with industry standards.

​